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Vaccines are not associated with autism: an evidence-based meta-analysis of case-control and cohort studies

source : nih.gov

Vaccines are not associated with autism: an evidence-based meta-analysis of case-control and cohort studies

There has been enormous debate regarding the possibility of a link between childhood vaccinations and the subsequent development of autism. This has in recent times become a major public health issue with vaccine preventable diseases increasing in the community due to the fear of a ‘link’ between vaccinations and autism. We performed a meta-analysis to summarise available evidence from case-control and cohort studies on this topic (MEDLINE, PubMed, EMBASE, Google Scholar up to April, 2014). Eligible studies assessed the relationship between vaccine administration and the subsequent development of autism or autism spectrum disorders (ASD). Two reviewers extracted data on study characteristics, methods, and outcomes. Disagreement was resolved by consensus with another author. Five cohort studies involving 1,256,407 children, and five case-control studies involving 9,920 children were included in this analysis. The cohort data revealed no relationship between vaccination and autism (OR: 0.99; 95% CI: 0.92 to 1.06) or ASD (OR: 0.91; 95% CI: 0.68 to 1.20), nor was there a relationship between autism and MMR (OR: 0.84; 95% CI: 0.70 to 1.01), or thimerosal (OR: 1.00; 95% CI: 0.77 to 1.31), or mercury (Hg) (OR: 1.00; 95% CI: 0.93 to 1.07). Similarly the case-control data found no evidence for increased risk of developing autism or ASD following MMR, Hg, or thimerosal exposure when grouped by condition (OR: 0.90, 95% CI: 0.83 to 0.98; p=0.02) or grouped by exposure type (OR: 0.85, 95% CI: 0.76 to 0.95; p=0.01). Findings of this meta-analysis suggest that vaccinations are not associated with the development of autism or autism spectrum disorder. Furthermore, the components of the vaccines (thimerosal or mercury) or multiple vaccines (MMR) are not associated with the development of autism or autism spectrum disorder.

Keywords:

Autism; Autism spectrum disorder; Immunisation; Mercury; Thimerosal; Vaccination; Vaccine.

Article: No scientific link between childhood vaccines and

Article: No scientific link between childhood vaccines and – By definition, the onset of autism occurs prior to age three. No clear cause of autism has been identified, although various possible associations have been examined.Several large-scale studies have found no evidence that the MMR vaccine causes ASD. Studies that disprove links between MMR and autism spectrum disorder. One study of more than 500 000 Danish children found no increased risk of ASD among those who had received the MMR vaccine compared with those who had not.For years scientists have said that there is no link between vaccines and autism. There are still many people who are reluctant to vaccinate. But, one woman has changed her mind about vaccines.

Autism: no link to vaccines & vaccinations | Raising – Extensive investigation into vaccines and autism has shown that there is no relationship between the two, causal or otherwise, and that vaccine ingredients do not cause autism. Vaccinologist Peter Hotez researched the growth of the false claim and concluded that its spread originated with Andrew Wakefield's fraudulent 1998 paper, with no prior paper supporting a link. Despite the scientific consensus for the absence of a relationship and the retracted paper, the anti-vaccination movement at larg"It is intensely sceptical about the possibility of error, but totally trusting about the possibility of fraud."1 Never has this been truer than of the 1998 Lancet paper that implied a link between the measles, mumps, and rubella (MMR) vaccine and a "new syndrome" of autism and bowel disease.⇓ Authored by Andrew Wakefield and 12The research, performed at the Statens Serum Institut (SSI), tracked 657,461 children born between 1999 and 2010 from 12 months of age until August 2013, and included 31,619 who had not received the (measles, mumps and rubella) MMR vaccine. It found that autism spectrum disorder (ASD) occurred equally in both sets of children, leading the study's authors to conclude that the MMR vaccine does not increase the risk of developing ASD.

Autism: no link to vaccines & vaccinations | Raising

When It Comes To Vaccines And Autism, Why Is It Hard To – Vaccines do not cause autism. Some people have had concerns that ASD might be linked to the vaccines children receive, but studies have shown that there is no link between receiving vaccines and developing ASD. In 2011, an Institute of Medicine (IOM) report external icon on eight vaccines given to children and adults found that with rare exceptions, these vaccines are very safe.Vaccines are not associated with autism: an evidence-based meta-analysis of case-control and cohort studies. There has been enormous debate regarding the possibility of a link between childhood vaccinations and the subsequent development of autism.Whistleblower Claims CDC Covered Up Data Showing Vaccine-Autism Link. were more likely than control children to have been vaccinated before 36 months of age." The association between

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